Depresion refractaria y alteracion vias fronto-limbicas
Autor: Daniel Serrani | Publicado:  27/04/2010 | Neurologia | |
Depresion refractaria y alteracion vias fronto-limbicas .3

El origen de las alteraciones micro-anatómicas en no remitentes no está claro del todo, pudiendo deberse a cambios vasculares subcorticales ya que hipocampo es particularmente sensible a los efectos del envejecimiento. La reducción del volumen de hipocampo correlaciona con duración de depresión (28). Como factor común de todas estas alteraciones esta el cambio en conexiones fronto-límbico-estriatales a nivel de fibras de sustancia blanca dando una vulnerabilidad para la depresión tarida y menor respuesta o remisión.

TABLA 3. Diferencias de anisotropía fraccional entre remitentes y no remitentes 

depresion_refractaria_frontolimbica/remitentes_anisotropia_fraccional

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