Publicado por: Dr KidronRicardo
Asunto: Re: Carbamazepine-induced reduction of blood levels of
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Carbamazepine-induced reduction of blood levels of haloperidol in chronic schizophrenia.
Kidron, Ricardo; Averbuch, Ilya; Klein, Ehud; Belmaker, Robert H.Biological Psychiatry. Vol 20(2), Feb 1985, 219-222.Nine 29–61 yr old chronic schizophrenics (Research Diagnostic Criteria) received a mean daily dose of 30 mg haloperidol; carbamazepine and placebo were also administered to Ss in a balanced double-blind random crossover design. Haloperidol levels were found to be significantly lower in carbamazepine- than in placebo-treated periods. However, carbamazepine did not appear to have a beneficial effect on chronic schizophrenia (Brief Psychiatric Rating Scale scores). (11 ref) (PsycINFO Database Record (c) 2009 APA, all rights reserved)
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